Solutions

Several infectious diseases have been the bane of the world health crisis, for which treatment and prevention are still being researched. Stellixir Biotech has expertise in assessing infectious diseases. The assessment of several therapeutic agents against viral and bacterial diseases that have developed resistance to the prevailing treatments is now being addressed by using various in vitro models. Formidable approaches in drug discovery are the future of fighting off infectious diseases. We have been able to assess the novel antimicrobials and anti-virals used as vaccines to prevent infectious diseases established using in vitro and in vivo models.

Our team of experts has designed experiments that are being used to test the efficacy of anti-infectives. It gives the impetus to support you to find proof in the early phases to select the key candidate drugs from animal models and allow free selection of infectious agents and parasites, enabling your infectious disease research. We also customize models that help your study using the latest model creation technology. Our microbiology services also provide space for pathogenic bacterial species further in your case. We cover the full spectrum from hospital-based studies to community outreach

Discovery Services:

We cover wide range of indicators:

Viral Indicators: COVID-19, SARS, H1N1, MERS and Ebola, Influenza, Hepatitis B and C

Bacterial Indicators: Expertise in multi drug-resistant infections as clA, cUTl, HAP/VAP, ABSSI, joint infections, osteomyelitis.

Available Assays for In-Vitro Antimicrobial and Anti-Viral Studies:

Antimicrobial In Vitro Bacterial Assays Include:

• MIC assays (minimum inhibitory concentration)
• MBC assays (minimum bactericidal concentration)
• Time-kill assays
• In Vitro pharmacokinetic and pharmacodynamics assays
• Resistance testing
• Cell-based assays (internalization and killing and biofilm assays)
• Immune modulation assays (ELISA, Luminex, and FACS)
• Metagenomics

In Vitro Anti-Viral Assays:

• COVID-19 protease inhibition assay
• TCID₅₀ assay
• EC₅₀ /CC₅₀ assay
• Plaque assays
• HAI assays (hemagglutination inhibition)
• Metagenomics

Available Models

Bacteria, including Gram positives and Gram-negatives covering ESKAPE pathogens

• Fungi including Candida, Aspergilli, and others
• Viruses including Respiratory Syncytial Virus (RSV)
• Parasites, including Toxoplasmosis gondii.